Get to know Optune Gio


What is Optune Gio?

Optune Gio is a wearable, portable, FDA-approved device. It treats a type of brain cancer called glioblastoma (GBM) in adult patients aged 22 years or older.

Ask your doctor about Optune Gio

Osmond, an Optune Gio user and Patient Ambassador

About Optune Gio

This may be the first time you’re hearing about a device that can treat GBM. Here are some things to know:

Optune Gio works by delivering Tumor Treating Fields (TTFields) therapy through adhesive patches that are placed on your head, called transducer arrays

Because Optune Gio is portable, you can receive continuous treatment almost anywhere

Optune Gio is small and lightweight, weighing just 2.7 pounds

With your doctor’s approval, you can use Optune Gio during your daily routine—at work, at social events, and even while traveling


More than 25,000 people have started Optune Gio

Kim is an Optune Gio user and Patient Ambassador

Optune Gio Has NCCN Category 1 Preferred Status

What does this mean?

The National Comprehensive Cancer Network® (NCCN®) is a not-for-profit alliance of leading cancer centers that is committed to advancing cancer care through the creation of NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®). These NCCN Guidelines® are used for patients and healthcare professionals around the world. The NCCN recommends treatments based on 3 Categories, with Category 1 being the highest recommendation.  


Tumor Treating Fields (Optune Gio) have been recognized as a Category 1 Preferred treatment for people newly diagnosed with GBM. Optune Gio has established itself as a Preferred standard of care because it has shown proven results, is considered a safe therapy, and, when appropriate, is an affordable treatment option.

NCCN makes no warranties of any kind whatsoever regarding their content, use or application and disclaims any responsibility for their application or use in any way.  


Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Central Nervous System Cancers V.1.2023. © National Comprehensive Cancer Network, Inc. 2023. All rights reserved. Accessed September 18, 2023. To view the most recent and complete version of the guideline, go online to

Explore the Optune Gio system

How long do I have to wear Optune Gio every day?

A large clinical study showed that Optune Gio should be turned on for at least 75% of the time, or 18 hours per day. This will help you get the best response from treatment.

You have the flexibility to decide which times of the day are best for you. Because Optune Gio is a wearable, portable device, you can take it with you wherever you go. 

Learn more about Optune Gio

Use this guide as a resource to learn more about Optune Gio and how it works.

Download the brochure

Ask your doctor about Optune Gio

This conversation guide can help you prepare for your next doctor’s appointment.

Download the guide

At-home treatment with Optune Gio

Discover Optune Gio, a treatment that can be used from the comfort of home.

Results with Optune Gio
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Optune Gio Buddy Program
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Important Safety Information

What is Optune Gio® approved to treat?

Optune Gio is a wearable, portable, FDA-approved device indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.

Newly diagnosed GBM

If you have newly diagnosed GBM, Optune Gio is used together with a chemotherapy called temozolomide (TMZ) if:

  • Your cancer is confirmed by your healthcare professional AND
  • You have had surgery to remove as much of the tumor as possible

Recurrent GBM

If your tumor has come back, Optune Gio can be used alone as an alternative to standard medical therapy if:

  • You have tried surgery and radiation and they did not work or are no longer working AND
  • You have tried chemotherapy and your GBM has been confirmed by your healthcare professional

Who should not use Optune Gio?

Optune Gio is not for everyone. Talk to your doctor if you have:

  • An implanted medical device (programmable shunt), skull defect (missing bone with no replacement), or bullet fragment. Optune Gio has not been tested in people with implanted electronic devices, which may cause the devices not to work properly, and Optune Gio has not been tested in people with skull defects or bullet fragments, which may cause Optune Gio not to work properly 
  • A known sensitivity to conductive hydrogels (the gel on the arrays placed on the scalp like the ones used on EKGs). When Optune Gio comes into contact with the skin, it may cause more redness and itching or may rarely cause a life-threatening allergic reaction

Do not use Optune Gio if you are pregnant or are planning to become pregnant. It is not known if Optune Gio is safe or effective during pregnancy.

What should I know before using Optune Gio?

Optune Gio should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure®, the maker of Optune Gio.

  • Do not use any parts that did not come with the Optune Gio Treatment Kit sent to you by Novocure or given to you by your doctor
  • Do not get the device or transducer arrays wet
  • If you have an underlying serious skin condition on the scalp, discuss with your doctor whether this may prevent or temporarily interfere with Optune Gio treatment

What are the possible side effects of Optune Gio?

Most common side effects of Optune Gio when used together with chemotherapy (temozolomide, or TMZ) were low blood platelet count, nausea, constipation, vomiting, tiredness, scalp irritation from the device, headache, seizure, and depression. The most common side effects when using Optune Gio alone were scalp irritation (redness and itchiness) and headache. Other side effects were malaise, muscle twitching, fall and skin ulcers. Talk to your doctor if you have any of these side effects or questions.


Please click here for the Optune Gio Instructions For Use (IFU) for complete information regarding the device’s indications, contraindications, warnings, and precautions.

Novocure Websites

This website is intended for people seeking information on Optune Gio.

On this site, videos and images identified as Optune Gio users, caregivers, or healthcare professionals depict actual patients, caregivers, and healthcare professionals.

Patient images reflect the health status of the patients at the time each photo or video was taken.


All rights reserved.

MyLink, MyNovocure, Novocure, and Optune Gio are registered trademarks of Novocure GmbH.

All other trademarks, registered or unregistered, are the property of their respective owners.

US-OPG-00063 v2.0 March 2024